SN-38 / irinotecan (TOP1) small-molecule series
- 화합물 7
- 관계 19
- SMILES 7/7
- Scaffold: 1
- Drug: 4
- Payload: 1
- Derivative: 1
Payload: sn38-adc-design
Camptothecin analog prodrug irinotecan → active SN-38; foundation for many TOP1 ADC payloads.
맵 열기 →패밀리 비교
sn38-irinotecan · exatecan-dxd
최대 4개 패밀리를 선택해 비교합니다.
Exatecan / DXd (TOP1 inhibitor) payload family
- 화합물 12
- 관계 57
- SMILES 12/12
- Linker: 2
- Scaffold: 1
- Payload: 1
- Derivative: 2
- ADC: 4
- Drug: 2
Payload: dxd
Camptothecin-derived TOP1 inhibitor payloads — DXd powers Enhertu and related ADC platforms.
맵 열기 →패밀리 간 overlap
- sn38-irinotecan ↔ exatecan-dxd · 평균 유사도(상위 쌍): 0.68
Core 화합물 Morgan 유사도
| SN-38 / irinotecan (TOP1) small-molecule series | Exatecan / DXd (TOP1 inhibitor) payload family | |
|---|---|---|
| SN-38 / irinotecan (TOP1) small-molecule series | 1.00 | 1.00 |
| Exatecan / DXd (TOP1 inhibitor) payload family | 1.00 | 1.00 |