All scaffolds
Migraine triptan series
편두통·triptan분석 없음Indole / tryptamine 5-HT1B/1D agonists — sumatriptan, rizatriptan and eletriptan.
맵 로딩 중…
Indole / tryptamine 5-HT1B/1D agonists — sumatriptan, rizatriptan and eletriptan.
맵 로딩 중…
약물명 · 2D 구조식 · SMILES · 역할 · 파생 출처 · core 유사도 · 특성(태그·노트)을 맵 위에 텍스트로 요약합니다. 행을 클릭하면 상세가 열립니다.
| 2D | 약물 / 화합물 | 역할 | 구조식 (SMILES) | 파생 출처 | Core 유사 | 특성 |
|---|---|---|---|---|---|---|
| Indole tryptamine pharmacophoretriptan-indole-core | Scaffold | C1=CC=C2C(=C1)C=CN2CCN | — | — | triptan · core · 5-HT1B/1D · Shared pharmacophore / core scaffold. Anchor for the Migraine triptan series lineage. | |
| Eletriptan (Relpax)eletriptan | Drug | CN1CCCC1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=… | Indole tryptamine pharmacophore | — | triptan · FDA · approved · Approved therapeutic. Eletriptan (Relpax) in this family map. | |
| Rizatriptan (Maxalt)rizatriptan | Drug | CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3 | Indole tryptamine pharmacophore | — | triptan · FDA · approved · Approved therapeutic. Rizatriptan (Maxalt) in this family map. | |
| Sumatriptan (Imitrex)sumatriptan | Drug | CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)C | Indole tryptamine pharmacophore | — | triptan · FDA · approved · 5-HT1B/1D · Approved therapeutic. Sumatriptan (Imitrex) in this family map. | |
| Methyl-indole triptan analogtriptan-methyl-indole | Derivative | CNCC1=CNC2=CC=CC=C21 | Indole tryptamine pharmacophore | — | SAR · SAR exploration node. Derived analog of parent node in Migraine triptan series. |
중심 core chemical에서 바깥 링으로 파생·drug·payload가 퍼지고, 점선·주황 chord는 drug 간 연결(spider web)입니다.
노드를 드래그해 배치를 조정하고, 클릭하면 2D 구조식이 표시됩니다.