All scaffolds
MS S1P modulator series
다발성경화·S1P분석 없음Sphingosine-1-phosphate receptor modulators — fingolimod, siponimod and ozanimod.
맵 로딩 중…
Sphingosine-1-phosphate receptor modulators — fingolimod, siponimod and ozanimod.
맵 로딩 중…
약물명 · 2D 구조식 · SMILES · 역할 · 파생 출처 · core 유사도 · 특성(태그·노트)을 맵 위에 텍스트로 요약합니다. 행을 클릭하면 상세가 열립니다.
| 2D | 약물 / 화합물 | 역할 | 구조식 (SMILES) | 파생 출처 | Core 유사 | 특성 |
|---|---|---|---|---|---|---|
| Sphingosine-like pharmacophores1p-sphingosine-core | Scaffold | CCCCCCCCCCCCC(C(CO)N)O | — | — | S1P · core · sphingosine · Shared pharmacophore / core scaffold. Anchor for the MS S1P modulator series lineage. | |
| Fingolimod (Gilenya)fingolimod | Drug | CCCCCCCC1=CC=C(C=C1)CCC(CO)(CO)N | Sphingosine-like pharmacophore | — | MS · FDA · approved · S1P1 · Approved therapeutic. Fingolimod (Gilenya) in this family map. | |
| Ozanimod (Zeposia)ozanimod | Drug | CC(C)OC1=C(C=C(C=C1)C2=NC(=NO2)C3=C4CCC(C4… | Sphingosine-like pharmacophore | — | MS · FDA · approved · S1P1/5 · Approved therapeutic. Ozanimod (Zeposia) in this family map. | |
| Siponimod (Mayzent)siponimod | Drug | CCC1=C(C=CC(=C1)C(=NOCC2=CC(=C(C=C2)C3CCCC… | Sphingosine-like pharmacophore | — | MS · FDA · approved · S1P1/5 · Approved therapeutic. Siponimod (Mayzent) in this family map. | |
| Des-hydroxy fingolimod analogfingolimod-des-hydroxy-analog | Derivative | CCCCCCCC1=CC=C(C=C1)CCC(C)N | Sphingosine-like pharmacophore | — | SAR · SAR exploration node. Derived analog of parent node in MS S1P modulator series. |
중심 core chemical에서 바깥 링으로 파생·drug·payload가 퍼지고, 점선·주황 chord는 drug 간 연결(spider web)입니다.
노드를 드래그해 배치를 조정하고, 클릭하면 2D 구조식이 표시됩니다.