daraxonrasib · kras-g12c · kras-g12d
최대 4개 패밀리를 선택해 비교합니다.
Payload: daraxon-payload-p1, daraxon-payload-p2, daraxon-payload-p3
KRAS G12C covalent inhibitor core and derived small molecules, ADC payloads, linkers, and assembled ADCs.
맵 열기 →Payload: kras-adc-payload-1
Shared acrylicamide / warhead chemotype from core scaffold to sotorasib, adagrasib, daraxonrasib and SAR analogs.
맵 열기 →Non-covalent and RAS(ON) chemotypes targeting KRAS G12D — MRTX1133, RMC-6236, RMC-9805 and SAR analogs.
맵 열기 →Morgan fingerprint, radius 2, 2048 bits, Tanimoto. This value does not predict potency, biological activity, safety, or clinical efficacy.
| Daraxonrasib scaffold family | KRAS G12C inhibitor chemical landscape | KRAS G12D / RAS(ON) inhibitor series | |
|---|---|---|---|
| Daraxonrasib scaffold family | 1.00 | 1.00 | 0.06 |
| KRAS G12C inhibitor chemical landscape | 1.00 | 1.00 | 0.06 |
| KRAS G12D / RAS(ON) inhibitor series | 0.06 | 0.06 | 1.00 |