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exatecan-dxd

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최대 4개 패밀리를 선택해 비교합니다.

ADC linker chemical familiesadc-linkers
ADHD stimulant / non-stimulant seriesadhd-stimulant
ALK / ROS1 TKI chemical seriesalk-inhibitors
ALS neuroprotectant seriesals-neuroprotectant
Antiepileptic drug chemical seriesantiepileptic-series
Atypical antipsychotic seriesatypical-antipsychotic
BCL-2 BH3-mimetic inhibitor seriesbcl2-inhibitors
BCR-ABL TKI chemical seriesbcr-abl-tki
Benzodiazepine GABA-A modulatorsbenzodiazepine-series
BRAF / MEK inhibitor chemical seriesbraf-mek
BTK inhibitor chemical seriesbtk-inhibitors
Calicheamicin enediyne payload familycalicheamicin
CDK4/6 inhibitor chemical seriescdk46-inhibitors
CGRP gepant migraine seriesmigraine-cgrp-gepant
Cognitive modulator seriescognitive-modulator-series
Daraxonrasib scaffold familydaraxonrasib
DM1 / maytansinoid payload familydm1
Duocarmycin CPI ADC payload seriesduocarmycin-payloads
EGFR tyrosine kinase inhibitor seriesegfr-inhibitors
Exatecan / DXd (TOP1 inhibitor) payload familyexatecan-dxd
GLP-1 / incretin agonist seriesglp1-agonists
JAK inhibitor chemical seriesjak-inhibitors
KRAS G12C inhibitor chemical landscapekras-g12c
KRAS G12D / RAS(ON) inhibitor serieskras-g12d
Migraine triptan seriesmigraine-triptan
MMAE (auristatin) payload familymmae
MS S1P modulator seriesms-s1p-modulator
Neuropathic gabapentinoid / SNRI seriesneuropathic-gabapentinoid
Parkinson dopaminergic / MAO-B seriesparkinson-dopaminergic
PARP inhibitor chemical seriesparp-inhibitors
PBD dimer ADC payload familypbd-payloads
PCSK9 inhibitor chemical & modality seriespcsk9-inhibitors
PI3K / AKT / mTOR inhibitor seriespi3k-akt-mtor
PROTAC / bifunctional degrader seriesprotac-degraders
RET / MET / NTRK oncogene TKI seriesret-met-ntrk
SGLT2 inhibitor seriessglt2-inhibitors
Sleep / hypnotic seriessleep-hypnotic
SN-38 / irinotecan (TOP1) small-molecule seriessn38-irinotecan
SSRI / SNRI antidepressant seriesssri-snri-series
Statin HMG-CoA reductase inhibitor seriesstatin-hmgcoa
Taxane diterpenoid seriestaxanes

보내기

Exatecan / DXd (TOP1 inhibitor) payload family

TOP1 inhibitor

화합물 12
관계 57
SMILES 12/12

Linker: 2
Scaffold: 1
Payload: 1
Derivative: 2
ADC: 4
Drug: 2

Payload: dxd

Camptothecin-derived TOP1 inhibitor payloads — DXd powers Enhertu and related ADC platforms.

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StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.

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