구조모아 (StructureMoa)

LIVE오늘…총 방문…패밀리…화합물…관계…

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PCSK9 inhibitor chemical & modality series

PCSK9 / LDL-C

화합물 9
관계 28
SMILES 9/9

Drug: 5
Derivative: 3
Scaffold: 1

Oral macrocyclic peptide PCSK9i (enlicitide / Lipfendra) mapped with injectable mAb (evolocumab, alirocumab) and siRNA (inclisiran) class peers for LDL-C lowering.

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ADC linker chemical families

ADC linker

화합물 8
관계 18
SMILES 8/8

Linker: 7
Scaffold: 1

Cleavable and non-cleavable linker scaffolds used across auristatin, maytansinoid, and TOP1 ADCs.

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패밀리 간 overlap

pcsk9-inhibitors ↔ adc-linkers · 평균 유사도(상위 쌍): 0.39

Core 화합물 Morgan 유사도

	PCSK9 inhibitor chemical & modality series	ADC linker chemical families
PCSK9 inhibitor chemical & modality series	1.00	0.13
ADC linker chemical families	0.13	1.00