mmae · dm1 · exatecan-dxd
최대 4개 패밀리를 선택해 비교합니다.
Payload: mmae, mmaf
Microtubule-disrupting auristatin payloads derived from dolastatin 10 — widely used in approved and clinical ADCs.
맵 열기 →Payload: dm1, dm4, sn38-payload-node
Maytansine-derived microtubule inhibitors — DM1 and DM4 used in Kadcyla and related ADCs.
맵 열기 →Payload: dxd
Camptothecin-derived TOP1 inhibitor payloads — DXd powers Enhertu and related ADC platforms.
맵 열기 →Morgan fingerprint, radius 2, 2048 bits, Tanimoto. This value does not predict potency, biological activity, safety, or clinical efficacy.
| MMAE (auristatin) payload family | DM1 / maytansinoid payload family | Exatecan / DXd (TOP1 inhibitor) payload family | |
|---|---|---|---|
| MMAE (auristatin) payload family | 1.00 | — | 0.14 |
| DM1 / maytansinoid payload family | — | 1.00 | — |
| Exatecan / DXd (TOP1 inhibitor) payload family | 0.14 | — | 1.00 |