mmae · duocarmycin-payloads · calicheamicin
최대 4개 패밀리를 선택해 비교합니다.
Payload: mmae, mmaf
Microtubule-disrupting auristatin payloads derived from dolastatin 10 — widely used in approved and clinical ADCs.
맵 열기 →Payload: duocarmycin-sa, seco-duocarmycin
Cyclopropapyrroloindole (CPI) DNA-alkylator payloads for ADCs — duocarmycin SA and seco forms.
맵 열기 →Payload: calicheamicin-gamma, nac-calicheamicin
Enediyne warhead for gemtuzumab ozogamicin (Mylotarg) and related ADCs.
맵 열기 →Morgan fingerprint, radius 2, 2048 bits, Tanimoto. This value does not predict potency, biological activity, safety, or clinical efficacy.
| MMAE (auristatin) payload family | Duocarmycin CPI ADC payload series | Calicheamicin enediyne payload family | |
|---|---|---|---|
| MMAE (auristatin) payload family | 1.00 | 0.18 | 0.06 |
| Duocarmycin CPI ADC payload series | 0.18 | 1.00 | 0.06 |
| Calicheamicin enediyne payload family | 0.06 | 0.06 | 1.00 |