Carbamazepine (Tegretol) structure · Antiepileptic · AED

Carbamazepine (Tegretol) 2D structure

Role: Drug
Family: Antiepileptic drug chemical series
Mechanism class: Antiepileptic · AED
Parent scaffold: Pyrrolidinone carboxamide core

Structure source: Catalog seed (external identifier on file)
PubChem CID: 2554
ChEMBL ID: CHEMBL108

How similarity is calculated

Hand-written analysis

Mechanism

카르바마제핀은 전압게이티드 Na 채널의 지연 불활성화를 도와 반복 발화를 줄입니다. HLA-B*1502와 SJS/TEN 위험이 있습니다. 자가유도 CYP3A로 농도가 시간에 따라 변합니다.

Medicinal chemistry

디벤즈아제핀 카르복사마이드입니다. 옥스카르바제핀·에스리카르바제핀은 케토/하이드록시 유도입니다.

Indication · context

초점 발작·삼차신경통이 고전 적응입니다. 라모트리진과 Na 채널 층은 같고 구조는 다릅니다.

SMILES

NC(=O)N1C2=CC=CC=C2C=CC3=CC=CC=C31

Related compounds

External IDs · BioMoa

PubChem CID 2554 CHEMBL108 BioMoa · BioMoa에서 검색 BioMoa · GABAergic / CNS BioMoa bridge Open on the family map Flow Structure table CNS Deep Analysis Mechanism class

StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.

Methodology

Carbamazepine (Tegretol) structure · mechanism