Drug · Antipsychotic · Antipsychotic · Verified drug
Aripiprazole (Abilify) structure · mechanism
Aripiprazole (Abilify) 2D structure
- Role
- Drug
- Mechanism class
- Antipsychotic
- Parent scaffold
- Piperazine aryl pharmacophore
- Indication
- Schizophrenia, bipolar, adjunct MDD · FDA/EMA
- Structure source
- Catalog seed
- FDA / EMA
- FDA/EMA
- ClinicalTrials.gov
- aripiprazole schizophrenia
- Regulatory status
- Approved · FDA/EMA · ClinicalTrials.gov · ClinicalTrials.gov
Hand-written analysis
Mechanism
아리피프라졸은 D2 부분작용과 5-HT1A 부분작용·5-HT2A 길항으로 설명되는 비정형 항정신병입니다. 대사 부담이 일부 약보다 낮습니다. 정좌불능이 흔합니다.
Medicinal chemistry
퀴놀리논 피페라진입니다. 올란자핀의 티에노벤조디아제핀과 다릅니다.
Indication · context
조현병·양극성·보조 우울. 수용체 프로파일로 독성을 비교합니다.
SMILES
C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)ClTags
Related compounds
External IDs · BioMoa
StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.