Rivastigmine (Exelon) structure · Cognition · dementia

Rivastigmine (Exelon) 2D structure

Role: Drug
Family: Cognitive modulator series
Mechanism class: Cognition · dementia
Parent scaffold: N-benzylpiperidine pharmacophore

Structure source: StructureMoa-defined exploratory node

How similarity is calculated

Hand-written analysis

Mechanism

리바스티그민은 AChE·BuChE를 카르바모일화하는 의사-비가역 저해제입니다. 패치 제형이 GI 부담을 줄입니다. 알츠하이머·파킨슨 치매 증상 완화입니다.

Medicinal chemistry

카르바메이트 페네틸 골격입니다. 도네페질의 인단온과 케모타입이 갈립니다.

Indication · context

경도~중등도 인지 증상. 메만틴(NMDA)과 병용 층이 다릅니다.

SMILES

CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C

Related compounds

External IDs · BioMoa

PubChem 검색 ChEMBL 검색 PubChem (SMILES)BioMoa · BioMoa에서 검색 BioMoa · GABAergic / CNS BioMoa bridge Open on the family map Flow Structure table CNS Deep Analysis Mechanism class

StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.

Methodology

Rivastigmine (Exelon) structure · mechanism