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StructureMoaOncology · CNS · cardio-metabolic · ADC catalog

Derivative · EGFR TKI · EGFR TKI · Exploratory analog (rule-generated)

EGFR C797S-resistance analog structure · mechanism

2D chemical structure

EGFR C797S-resistance analog 2D structure

Role
Derivative
Mechanism class
EGFR TKI
Parent scaffold
Osimertinib (Tagrisso)
Structure source
StructureMoa-defined exploratory analog

How similarity is calculated

SMILES

COC1=C(NC2=NC=CC(=N2)C2=CC=CC=C2)C=C(C=C1)NC(=O)C(=C)C

Tags

SARC797Sresistance

Related compounds

External IDs · BioMoa

PubChem 검색ChEMBL 검색PubChem (SMILES)BioMoa · BioMoa에서 검색BioMoa · EGFR TKI 프로그램BioMoa bridgeOpen on the family mapFlowStructure tableMechanism class

StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.

Methodology