Scaffold · TOP1 inhibitor · TOP1 inhibitor · Abstract pharmacophore
Camptothecin / exatecan core structure · mechanism
Lactone-bearing TOP1 inhibitor pharmacophore.
Camptothecin / exatecan core 2D structure
- Role
- Scaffold
- Mechanism class
- TOP1 inhibitor
- Structure source
- StructureMoa-defined abstract pharmacophore
SMILES
CC1=C2C(=C(C=C1)O)C(=O)OC2=CC3=C(C=CC=C3)NTags
Related compounds
External IDs · BioMoa
StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.