ADC · TOP1 inhibitor · TOP1 inhibitor · ADC
Dato-DXd (TROP2, alt node) structure · mechanism
Dato-DXd (TROP2, alt node) 2D structure
- Role
- ADC
- Mechanism class
- TOP1 inhibitor
- Parent scaffold
- DXd membrane-permeability SAR analog
- Structure source
- StructureMoa-defined exploratory ADC node
SMILES
CC1=C2C(=C(C=C1)O)C(=O)OC2=CC3=C(C=CC=C3)NC(=O)CCNC(=O)CTags
Related compounds
External IDs · BioMoa
StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.