Ubrogepant (Ubrelvy) structure · Migraine · CGRP gepant

Ubrogepant (Ubrelvy) 2D structure

Role: Drug
Family: CGRP gepant migraine series
Mechanism class: Migraine · CGRP gepant
Parent scaffold: CGRP urea / amide pharmacophore
Indication: Acute migraine · FDA

Structure source: Catalog seed
FDA / EMA: FDA
ClinicalTrials.gov: ubrogepant migraine
Regulatory status: Approved · FDA · ClinicalTrials.gov · ClinicalTrials.gov

How similarity is calculated

Hand-written analysis

Mechanism

우브로게판트는 CGRP 수용체 소분자 길항(gepant)입니다. 혈관수축 없이 편두통 급성에 쓰입니다. 트립탄 금기 환자에서 대안이 됩니다.

Medicinal chemistry

스피로 피페리디논 gepant 골격입니다. 리메게판트·아토게판트와 적응(급성 vs 예방)이 갈립니다.

Indication · context

편두통 급성. /class/cgrp-gepant에서 세 약을 비교합니다.

SMILES

CC(C)(C)NC(=O)N1CCN(CC1)C2=NC3=CC=CC=C3N2C4=CC=C(C=C4)F

Related compounds

External IDs · BioMoa

PubChem 검색 ChEMBL 검색 PubChem (SMILES)BioMoa · CNS / CGRP gepant BioMoa bridge Open on the family map Flow Structure table CNS Deep Analysis Mechanism class

StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.

Methodology

Ubrogepant (Ubrelvy) structure · mechanism