Drug · Migraine · triptan · Migraine · triptan · Verified drug
Sumatriptan (Imitrex) structure · mechanism
Sumatriptan (Imitrex) 2D structure
- Role
- Drug
- Family
- Migraine triptan series
- Mechanism class
- Migraine · triptan
- Parent scaffold
- Indole tryptamine pharmacophore
- Indication
- Acute migraine · FDA/EMA
- Structure source
- Catalog seed
- FDA / EMA
- FDA/EMA
- ClinicalTrials.gov
- sumatriptan migraine
- Regulatory status
- Approved · FDA/EMA · ClinicalTrials.gov · ClinicalTrials.gov
Hand-written analysis
Mechanism
수마트립탄은 5-HT1B/1D 작용 트립탄입니다. 뇌혈관 수축과 CGRP 등 펩타이드 방출 억제로 편두통 급성을 돕습니다. 관상동맥 질환에서 금기입니다.
Medicinal chemistry
인돌 에틸아민에 설폰아마이드가 있습니다. 리자트립탄 등과 흡수·지속이 다릅니다.
Indication · context
편두통 급성. gepant(CGRP 길항)와 표적 층이 다릅니다.
SMILES
CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CCN(C)CTags
Related compounds
External IDs · BioMoa
StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.