Drug · Neuropathic · gabapentinoid · Neuropathic · gabapentinoid · Verified drug
Pregabalin (Lyrica) structure · mechanism
Pregabalin (Lyrica) 2D structure
- Role
- Drug
- Mechanism class
- Neuropathic · gabapentinoid
- Parent scaffold
- Gabapentinoid amino-acid core
- Indication
- Neuropathic pain, fibromyalgia, seizures · FDA/EMA
- Structure source
- Catalog seed
- FDA / EMA
- FDA/EMA
- ClinicalTrials.gov
- pregabalin neuropathic pain
- Regulatory status
- Approved · FDA/EMA · ClinicalTrials.gov · ClinicalTrials.gov
Hand-written analysis
Mechanism
프레가발린도 α2δ 리간드입니다. 가바펜틴보다 선형 PK와 높은 생체이용이 장점입니다. 어지럼·부종·남용 가능성을 설명합니다.
Medicinal chemistry
이소부틸 GABA 유사체입니다. 기전 층은 가바펜틴과 같습니다.
Indication · context
신경병증·섬유근육통·일부 불안. /class/neuropathic의 대표입니다.
SMILES
CC(C)C[C@H](N)CC(=O)OTags
Related compounds
External IDs · BioMoa
StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.