Canagliflozin (Invokana) structure · SGLT2 inhibitor

Canagliflozin (Invokana) 2D structure

Role: Drug
Family: SGLT2 inhibitor series
Mechanism class: SGLT2 inhibitor
Parent scaffold: C-glucoside SGLT2 pharmacophore

Structure source: Catalog seed

How similarity is calculated

Hand-written analysis

Mechanism

카나글리플로진은 SGLT2 저해 C-글루코사이드입니다. 포도당 배설과 심신 이득 층은 엠파글리플로진과 같습니다. 절단 위험 등 약별 안전 이슈를 라벨에서 확인합니다.

Medicinal chemistry

티오펜 아릴 C-글루코사이드입니다. 엠파글리플로진·다파글리플로진과 아릴이 다릅니다.

Indication · context

2형 당뇨가 중심 적응입니다. SGLT2 허브에서 세 약을 비교합니다.

SMILES

CCOC1=CC=C(C=C1)CC2=CC(=CC(=C2)C3=CC=C(C=C3)F)C4=CC(=CC(=C4)C5=CC=CC=C5)OCC6C(C(C(C(O6)CO)O)O)O

Related compounds

External IDs · BioMoa

PubChem 검색 ChEMBL 검색 PubChem (SMILES)BioMoa · BioMoa에서 검색 BioMoa · SGLT2 inhibitor BioMoa bridge Open on the family map Flow Structure table Mechanism class

StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.

Methodology

Canagliflozin (Invokana) structure · mechanism