| Phenethylamine pharmacophoreAbstract pharmacophoreadhd-phenethylamine-corePage | Scaffold | NCCC1=CC=CC=C1 | — | — | ADHD · core · monoamine · Shared pharmacophore / core scaffold. Anchor for the ADHD stimulant / non-stimulant series… |
| Amphetamine (Adderall component)Verified drugamphetaminePage | Drug | CC(CC1=CC=CC=C1)N | Phenethylamine pharmacophore | — | ADHD · FDA · approved · DAT/NET release · Approved therapeutic. Amphetamine (Adderall component) in this family map. |
| Atomoxetine (Strattera)Verified drugatomoxetinePage | Drug | CC1=CC=CC=C1OC(CCNC)C2=CC=CC=C2 | Phenethylamine pharmacophore | — | ADHD · FDA · approved · NET inhibitor · Approved therapeutic. Atomoxetine (Strattera) in this family map. |
| Guanfacine (Intuniv)Verified drugguanfacinePage | Drug | NC(=N)NC1=CC=CC(Cl)=C1Cl | Phenethylamine pharmacophore | — | ADHD · FDA · approved · α2A agonist · non-stimulant · Approved therapeutic. Guanfacine (Intuniv) in this family map. |
| Lisdexamfetamine (Vyvanse)Verified druglisdexamfetaminePage | Drug | CC(CC1=CC=CC=C1)NC(=O)[C@@H](N)CCCCN | Phenethylamine pharmacophore | — | ADHD · FDA · approved · prodrug · amphetamine · Approved therapeutic. Lisdexamfetamine (Vyvanse) in this family map. |
| Methylphenidate (Ritalin)Verified drugmethylphenidatePage | Drug | COC(=O)C(C1CCCCN1)C2=CC=CC=C2 | Phenethylamine pharmacophore | — | ADHD · FDA · approved · DAT inhibitor · Approved therapeutic. Methylphenidate (Ritalin) in this family map. |
| Viloxazine (Qelbree)Verified drugviloxazinePage | Drug | CCOC1=CC=CC=C1OC(C)CN | Phenethylamine pharmacophore | — | ADHD · FDA · approved · NET inhibitor · non-stimulant · Approved therapeutic. Viloxazine (Qelbree) in this family map. |
| Fluoro-phenethylamine analogExploratory analog (rule-generated)adhd-fluoro-phenethylaminePage | Derivative | CC(CC1=CC=C(C=C1)F)N | Phenethylamine pharmacophore | — | SAR · F-scan · SAR exploration node. Derived analog of parent node in ADHD stimulant / non-stimulant seri… |