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StructureMoaOncology · CNS · cardio-metabolic · ADC catalog

Drug · BCL-2 inhibitor · BCL-2 inhibitor · Known compound

Lisaftoclax (APG-2575) structure · mechanism

2D chemical structure

Lisaftoclax (APG-2575) 2D structure

Role
Drug
Mechanism class
BCL-2 inhibitor
Parent scaffold
BH3-mimetic scaffold
Structure source
Catalog seed

How similarity is calculated

SMILES

CC1(CCC(=C(C1)c2ccc(Cl)cc2)CN3CCN(CC3)c4ccc(C(=O)NS(=O)(=O)c5ccc(NCCCN6CCOCC6)cc5)c(OC)c4)C

Tags

clinicalBCL-2

Related compounds

External IDs · BioMoa

PubChem 검색ChEMBL 검색PubChem (SMILES)BioMoa · BioMoa에서 검색BioMoa · BCL-2 inhibitorBioMoa bridgeOpen on the family mapFlowStructure tableMechanism class

StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.

Methodology