Derivative · KRAS inhibitor · KRAS inhibitor · Exploratory analog
KRAS PROTAC hybrid 1 structure · mechanism
KRAS PROTAC hybrid 1 2D structure
- Role
- Derivative
- Mechanism class
- KRAS inhibitor
- Parent scaffold
- Sotorasib (Lumakras)
- Structure source
- StructureMoa-defined exploratory node
SMILES
C[C@H]1CN(C(=O)C2=C(NC3=CC=CC(F)=C3)N=C(N2)C2=CC=C(C=C2)C#N)C[C@@H]1CNC(=O)CCN3CCN(CC3)CTags
Related compounds
External IDs · BioMoa
StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.