Drug · Antidepressant · SSRI/SNRI · Antidepressant · SSRI/SNRI · Verified drug
Escitalopram (Lexapro) structure · mechanism
Escitalopram (Lexapro) 2D structure
- Role
- Drug
- Mechanism class
- Antidepressant · SSRI/SNRI
- Aliases
- lexapro
- Parent scaffold
- Aryloxy-propylamine core
- Indication
- MDD, GAD · FDA/EMA
- Structure source
- Catalog seed (external identifier on file)
- PubChem CID
- 146570
- ChEMBL ID
- CHEMBL1508
- FDA / EMA
- FDA/EMA
- ClinicalTrials.gov
- escitalopram MDD
- Regulatory status
- Approved · FDA/EMA · ClinicalTrials.gov · ClinicalTrials.gov
Hand-written analysis
Mechanism
에스시탈로프람은 시탈로프람의 S-에난티오머로 SERT에 고선택입니다. R-에난티오머가 결합을 방해한다는 알로스테릭 설명이 있습니다. QTc는 용량과 함께 봅니다.
Medicinal chemistry
프탈란 카보나이트릴 골격입니다. 라세미 시탈로프람과 입체화학만 갈립니다.
Indication · context
우울·범불안 등에서 내약성 SSRI로 많이 씁니다. 계열 허브의 대표 구조입니다.
SMILES
CN[C@@H](CCCOC1=CC=C(C=C1)C#N)C2=CC=C(C=C2)FTags
Related compounds
Comparisons · briefs
External IDs · BioMoa
StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.