Sertraline (Zoloft) structure · Antidepressant · SSRI/SNRI

Sertraline (Zoloft) 2D structure

Role: Drug
Family: SSRI / SNRI antidepressant series
Mechanism class: Antidepressant · SSRI/SNRI
Aliases: zoloft
Parent scaffold: Aryloxy-propylamine core

Structure source: Catalog seed (external identifier on file)
PubChem CID: 68617
ChEMBL ID: CHEMBL809

How similarity is calculated

Hand-written analysis

Mechanism

설트랄린도 SERT 선택 재흡수 차단 SSRI입니다. 도파민 재흡수에 약한 여유도가 있다는 설명이 있으나 임상 용량에서는 SERT가 주입니다. GI 부작용이 초기에 흔합니다.

Medicinal chemistry

테트라린 아민에 디클로로페닐이 붙습니다. 플루옥세틴과 케모타입이 다릅니다.

Indication · context

우울·불안·PTSD 등 SSRI 적응입니다. SSRI vs SNRI 비교 문서의 한 축입니다.

SMILES

CN[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C[C@H]1C

Related compounds

Comparisons · briefs

External IDs · BioMoa

PubChem CID 68617 CHEMBL809 BioMoa · CNS / SSRI BioMoa bridge Open on the family map Flow Structure table CNS Deep Analysis Mechanism class

StructureMoa is a chemical-structure exploration tool. Structural similarity, clustering, and SAR relationships are intended for research exploration and do not establish shared potency, selectivity, safety, efficacy, or clinical performance.

Methodology

Sertraline (Zoloft) structure · mechanism